Fatty Acids

Omega-3 (EPA + DHA)

The fatty acids your brain and heart depend on.

Omega-3 fatty acids EPA and DHA reduce chronic inflammation, lower triglycerides, and support brain structure throughout life. Large cohort studies consistently link higher omega-3 blood levels with reduced cardiovascular mortality and slower cognitive decline. The Framingham Heart Study found that participants in the top quartile of DHA levels had a 47% lower risk of developing dementia.

Dosage

RDA: 250-500mg combined EPA and DHA daily (AHA recommendation)

Optimal for longevity: Longevity researchers suggest 1,000-2,000mg combined EPA and DHA daily, targeting an Omega-3 Index of 8-12%.

Deficiency signs

~68% of Americans have an Omega-3 Index below 4%, considered high risk

  • Dry, flaky skin
  • Difficulty concentrating or brain fog
  • Joint stiffness and pain
  • Mood changes or low mood

Top food sources

Atlantic mackerel (3 oz)2,670mg
Wild salmon (3 oz)1,800mg
Sardines (3 oz)1,360mg
Anchovies (3 oz)1,290mg
Herring (3 oz)1,710mg

Research

Harris WS et al. (2018). The Omega-3 Index and relative risk for coronary heart disease mortality. Atherosclerosis, 262, 21-27.

Track your omega-3 (epa + dha) intake

Biohack logs omega-3 (epa + dha) alongside 22 other longevity nutrients in every meal.

Related reading

The 23 Nutrients That Predict How Long You Live

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Your Omega Ratio Is Probably Off. Here Is Why That Matters.

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